Ectodysplasin A (EDA) (Middle Region) Peptide
EDA
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Ectodysplasin A (EDA) products
- Ectodysplasin A (EDA)
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-EDA antibody (Catalog #: ARP44519_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Ectodysplasin A (EDA)
- Synonyms
- ECTD1 Peptide, ED1 Peptide, ED1-A1 Peptide, ED1-A2 Peptide, EDA-A1 Peptide, EDA-A2 Peptide, EDA1 Peptide, EDA2 Peptide, HED Peptide, HED1 Peptide, ODT1 Peptide, STHAGX1 Peptide, XHED Peptide, XLHED Peptide, si:ch73-223d24.5 Peptide, Ed1 Peptide, Eda-A1 Peptide, Eda-A2 Peptide, Ta Peptide, tabby Peptide, RGD1563178 Peptide, ectodysplasin A Peptide, ectodysplasin-A Peptide, EDA Peptide, eda Peptide, Eda Peptide
- Background
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EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. It belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.
Alias Symbols: ED1, ED1-A1, ED1-A2, EDA1, EDA2, HED, XHED, XLHED, ODT1, STHAGX1
Protein Interaction Partner: EDA,EDA2R,EDAR,FURIN,EDAR
Protein Size: 389 - Molecular Weight
- 41 kDa
- Gene ID
- 1896
- NCBI Accession
- NM_001005609, NP_001005609
- UniProt
- B7ZLU4
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