ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) Peptide
EDEM1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all EDEM1 products
- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-EDEM1 antibody (Catalog #: ARP47054_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
- Synonyms
- zgc:55816 Peptide, edem Peptide, EDEM1 Peptide, EDEM Peptide, A130059K23Rik Peptide, mKIAA0212 Peptide, RGD1563633 Peptide, ER degradation enhancer, mannosidase alpha-like 1 Peptide, ER degradation enhancing alpha-mannosidase like protein 1 Peptide, ER degradation-enhancing alpha-mannosidase-like protein 1 Peptide, ER degradation enhancing alpha-mannosidase like protein 1 L homeolog Peptide, edem1 Peptide, EDEM1 Peptide, LOC100637820 Peptide, edem1.L Peptide, Edem1 Peptide
- Background
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EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.
Alias Symbols: EDEM, KIAA0212
Protein Interaction Partner: CANX,BZW1,CANX
Protein Size: 657 - Molecular Weight
- 74 kDa
- Gene ID
- 9695
- NCBI Accession
- NM_014674, NP_055489
- UniProt
- Q92611
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