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Eukaryotic Translation Initiation Factor 2, Subunit 3 Gamma, 52kDa (EIF2S3) Peptide

EIF2S3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN976219
  • Target See all EIF2S3 products
    EIF2S3 (Eukaryotic Translation Initiation Factor 2, Subunit 3 Gamma, 52kDa (EIF2S3))
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-EIF2S3 antibody (Catalog #: ARP46057_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    EIF2S3 (Eukaryotic Translation Initiation Factor 2, Subunit 3 Gamma, 52kDa (EIF2S3))
    Synonyms
    EIF2 Peptide, EIF2G Peptide, EIF2gamma Peptide, eIF-2gA Peptide, Su(var)3-9 Peptide, fi03g03 Peptide, wu:fi03g03 Peptide, wu:fi37d04 Peptide, zgc:63805 Peptide, EIF2S3 Peptide, eif2 Peptide, eif2g Peptide, eif2s3y Peptide, eif2gamma Peptide, Eif2g Peptide, Eif2s3 Peptide, PP42 Peptide, ENSMUSG00000079297 Peptide, eukaryotic translation initiation factor 2 subunit gamma Peptide, eukaryotic translation initiation factor 2, subunit 3 gamma Peptide, eukaryotic translation initiation factor 2 subunit gamma S homeolog Peptide, putative eukaryotic translation initiation factor 2 subunit 3-like protein Peptide, eukaryotic translation initiation factor 2 subunit 3 Peptide, predicted pseudogene 2223 Peptide, EIF2S3 Peptide, eif2s3 Peptide, eif2s3.S Peptide, LOC738402 Peptide, LOC100179499 Peptide, LOC100624149 Peptide, Eif2s3 Peptide, Gm2223 Peptide
    Background
    EIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

    Alias Symbols: EIF2, EIF2G, EIF2gamma, eIF-2gA

    Protein Interaction Partner: CTCF,H3F3A,METAP2,NDRG1,CASP4,EIF1B

    Protein Size: 472
    Molecular Weight
    51 kDa
    Gene ID
    1968
    NCBI Accession
    NM_001415, NP_001406
    UniProt
    P41091
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