Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) (N-Term) Peptide
EIF4G2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all EIF4G2 products
- EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-EIF4G2 antibody (Catalog #: ARP40362_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))
- Synonyms
- AAG1 Peptide, DAP5 Peptide, NAT1 Peptide, P97 Peptide, NAT1B Peptide, eif4g2 Peptide, hm:zeh1307 Peptide, wu:fa14h01 Peptide, wu:fb44h01 Peptide, wu:fb59c06 Peptide, wu:fc21b05 Peptide, EIF4G2 Peptide, AA589388 Peptide, DAP-5 Peptide, E130105L11Rik Peptide, Nat1 Peptide, Natm1 Peptide, p97 Peptide, NAT1A Peptide, im:7148615 Peptide, wu:fb81f07 Peptide, wu:fb82b06 Peptide, wu:fb98h08 Peptide, dap5 Peptide, eif4g2.L Peptide, nat1 Peptide, eukaryotic translation initiation factor 4 gamma 2 Peptide, eukaryotic translation initiation factor 4, gamma 2b Peptide, eukaryotic translation initiation factor 4, gamma 2 Peptide, eukaryotic translation initiation factor 4 gamma, 2 Peptide, eIF4G-related protein NAT1 Peptide, eukaryotic translation initiation factor 4, gamma 2a Peptide, eukaryotic translation initiation factor 4 gamma, 2 S homeolog Peptide, EIF4G2 Peptide, eif4g2b Peptide, Eif4g2 Peptide, nat1 Peptide, eif4g2a Peptide, eif4g2.S Peptide
- Background
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Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. EIF4G2 shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, EIF4G2 functions as a general repressor of translation by forming translationally inactive complexes. Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Alias Symbols: AAG1, DAP5, FLJ41344, NAT1, p97, P97
Protein Interaction Partner: NCBP1,CASP3,EIF2S2,EIF3A,EIF4A1,EIF4A2,EIF4E,EIF5,MKNK1,NCBP1,SKIL,EIF3A,EIF3F,EIF4A1,EIF4A2,EIF4E,MAGEA6,MKNK1
Protein Size: 907 - Molecular Weight
- 102 kDa
- Gene ID
- 1982
- NCBI Accession
- NM_001418, NP_001409
- UniProt
- P78344
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