Ets Variant 5 (ETV5) Peptide
ETV5
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ETV5 products
- ETV5 (Ets Variant 5 (ETV5))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ETV5 antibody (Catalog #: ARP38468_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ETV5 (Ets Variant 5 (ETV5))
- Synonyms
- ERM Peptide, etv5 Peptide, fj87h10 Peptide, id:ibd5133 Peptide, wu:fj87h10 Peptide, zgc:55647 Peptide, 1110005E01Rik Peptide, 8430401F14Rik Peptide, ETS variant 5 Peptide, ets variant 5 Peptide, ets variant 5a Peptide, ETV5 Peptide, Etv5 Peptide, etv5a Peptide
- Background
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ETV5 Contains 1 ETS DNA-binding domain and belongs to the ETS family. The ETV5 gene expression is regulated by the conventional PKC (cPKC) pathway.ETV5 is subject to SUMO modification and this post-translational modification causes inhibition of transcription-enhancing activity Phosphorylated ETV5 and the actin cytoskeleton regulate CD44-mediated hyaluronan binding in myeloid cells. ERMs (ezrin/radixin/moesin) function as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases. ETV5 can cooperate with c-Jun and has a role in progression of breast cancer.
Alias Symbols: ERM
Protein Interaction Partner: AR,AR
Protein Size: 510 - Molecular Weight
- 58 kDa
- Gene ID
- 2119
- NCBI Accession
- NM_004454, NP_004445
- UniProt
- P41161
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