Ets Variant 6 (ETV6) (N-Term) Peptide
ETV6
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ETV6 products
- ETV6 (Ets Variant 6 (ETV6))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ETV6 antibody (Catalog #: P100806_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ETV6 (Ets Variant 6 (ETV6))
- Synonyms
- etv-6 Peptide, tel Peptide, tel/abl Peptide, AW123102 Peptide, AW557856 Peptide, Tel Peptide, TEL Peptide, id:ibd2308 Peptide, TEL/ABL Peptide, cmlc2 Peptide, mylc2a Peptide, zgc:92755 Peptide, ETS variant 6 Peptide, ets variant 6 Peptide, myosin, light chain 7, regulatory Peptide, etv6 Peptide, Etv6 Peptide, ETV6 Peptide, myl7 Peptide
- Background
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ETV6 (ETS-related protein Tel1, ETS translocation variant 6 , Tel) is an ETS family transcription factor. it contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TEL, TEL/ABL
Protein Interaction Partner: ETV6,FLI1,HDAC9,KAT5,L3MBTL,SIN3A,SMURF1,SUMO1,UBE2I,ACTA1,CRKL,ETV6,FBXL6,FLI1,GAB2,GRB2,HDAC9,IRF8,KAT5,L3MBTL,SKP1,UBC
Protein Size: 452 - Molecular Weight
- 53 kDa
- Gene ID
- 2120
- NCBI Accession
- NM_001987, NP_001978
- UniProt
- P41212
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