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Eyes Absent Homolog 1 (EYA1) (Middle Region) Peptide

EYA1 Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN976533
  • Target See all EYA1 products
    EYA1 (Eyes Absent Homolog 1 (EYA1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-EYA1 antibody (Catalog #: ARP32434_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    EYA1 (Eyes Absent Homolog 1 (EYA1))
    Synonyms
    EYA1 Peptide, bop Peptide, bor Peptide, XEya1 Peptide, wu:fc13c10 Peptide, zgc:100770 Peptide, BOP Peptide, BOR Peptide, BOS1 Peptide, EYA transcriptional coactivator and phosphatase 1 Peptide, EYA transcriptional coactivator and phosphatase 1 L homeolog Peptide, EYA1 Peptide, eya1 Peptide, Eya1 Peptide, eya1.L Peptide
    Background
    EYA1 is a member of the eyes absent (EYA) family of proteins. EYA1 may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator.This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Four transcript variants encoding three distinct isoforms have been identified for this gene.

    Alias Symbols: BOP, BOR, MGC141875

    Protein Interaction Partner: DACH1,GNAI2,GNAZ,SIX1,SIX2,SIX3,SIX1

    Protein Size: 557
    Molecular Weight
    61 kDa
    Gene ID
    2138
    NCBI Accession
    NM_172060, NP_742057
    UniProt
    Q99502
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