Fibroblast Growth Factor Receptor 2 (FGFR2) (Middle Region) Peptide
FGFR2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FGFR2 products
- FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KHVEKNGSKY GPDGLPYLKV LKHSGINSSN AEVLALFNVT EADAGEYICK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FGFR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Fibroblast Growth Factor Receptor 2 (FGFR2) peptide
FGFR2 Reactivity: Human, Mouse, Cow, Dog, Pig, Rat Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
- Synonyms
- FGFR2 Peptide, FGFR2IIIb Peptide, bek Peptide, bfr-1 Peptide, cd332 Peptide, cek3 Peptide, cfd1 Peptide, ect1 Peptide, fgfr-2 Peptide, jws Peptide, k-sam Peptide, kgfr Peptide, tk14 Peptide, tk25 Peptide, xfgfr2 Peptide, DKFZp469H1521 Peptide, BBDS Peptide, BEK Peptide, BFR-1 Peptide, CD332 Peptide, CEK3 Peptide, CFD1 Peptide, ECT1 Peptide, JWS Peptide, K-SAM Peptide, KGFR Peptide, TK14 Peptide, TK25 Peptide, AU043015 Peptide, AW556123 Peptide, Bek Peptide, Fgfr-2 Peptide, Fgfr-7 Peptide, Fgfr7 Peptide, KGFRTr Peptide, svs Peptide, FGF-R Peptide, fgfr72IIIb Peptide, FGFR Peptide, fc56c05 Peptide, wu:fc56c05 Peptide, fibroblast growth factor receptor 2 Peptide, fibroblast growth factor receptor 2 L homeolog Peptide, FGFR2 Peptide, LOC100084641 Peptide, fgfr2 Peptide, Fgfr2 Peptide, fgfr2.L Peptide
- Background
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The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alias Symbols: BEK, BFR-1, CD332, CEK3, CFD1, ECT1, FLJ98662, JWS, K-SAM, KGFR, TK14, TK25
Protein Size: 705 - Molecular Weight
- 78 kDa
- Gene ID
- 2263
- NCBI Accession
- NM_022970, NP_075259
- UniProt
- P21802
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