Frizzled Family Receptor 8 (FZD8) (N-Term) Peptide
FZD8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FZD8 products
- FZD8 (Frizzled Family Receptor 8 (FZD8))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FZD8 antibody (Catalog #: ARP41283_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FZD8 (Frizzled Family Receptor 8 (FZD8))
- Synonyms
- FZ-8 Peptide, hFZ8 Peptide, FZD8 Peptide, Fz-8 Peptide, frizzled8 Peptide, xfz8 Peptide, Xfz8 Peptide, frizzled-8 Peptide, hfz8 Peptide, Fz8 Peptide, fzd8 Peptide, fz5 Peptide, fz8a Peptide, fzc Peptide, wu:fd02c05 Peptide, zg05 Peptide, ZG06 Peptide, Zfz8b Peptide, fz6 Peptide, fz8b Peptide, fzA Peptide, ik:tdsubc_1e1 Peptide, xx:tdsubc_1e1 Peptide, zfzA Peptide, frizzled class receptor 8 Peptide, frizzled class receptor 8 S homeolog Peptide, frizzled class receptor 8 L homeolog Peptide, frizzled class receptor 8a Peptide, frizzled class receptor 8b Peptide, FZD8 Peptide, fzd8.S Peptide, fzd8 Peptide, Fzd8 Peptide, fzd8.L Peptide, fzd8a Peptide, fzd8b Peptide
- Background
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FZD8 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
Alias Symbols: FZ-8, hFZ8
Protein Interaction Partner: RYK,WNT1,GOPC,LRP5,LRP6,RYK,WNT1,LRP5,LRP6,WNT1
Protein Size: 694 - Molecular Weight
- 73 kDa
- Gene ID
- 8325
- NCBI Accession
- NM_031866, NP_114072
- UniProt
- Q9H461
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