GATA Zinc Finger Domain Containing 2B (GATAD2B) Peptide
GATAD2B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GATAD2B products
- GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GATAD2B antibody (Catalog #: ARP39429_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))
- Synonyms
- GATAD2B Peptide, MRD18 Peptide, P66beta Peptide, RP11-216N14.6 Peptide, p68 Peptide, AL118180 Peptide, C430014D17Rik Peptide, mKIAA1150 Peptide, RGD1308533 Peptide, GATA zinc finger domain containing 2B Peptide, GATAD2B Peptide, gatad2b Peptide, Gatad2b Peptide
- Background
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Hp66beta (GATAD2B), previously identified as a component of the human MeCP1 complex, is a second member of a p66 gene family (hp66alpha and hp66beta). Both proteins interact with MBD2 and MBD3 functionally and biochemically. Both factors function in synergy, since knocking-down p66alpha affects the repressive function of p66beta and vice versa. Furthermore, confocal microscopy shows a nuclear colocalization of hp66alpha with hp66beta and MBD2 in a speckled pattern. These two highly related mammalian p66 proteins display overlapping functions and are involved in methylation dependent transcriptional repression.
Alias Symbols: P66beta, RP11-216N14.6
Protein Interaction Partner: KAT2B,MBD2,MBD3,SMAD2,FOXP1,FOXP2,Foxp2,HDAC1,HDAC2,MBD2,MBD3,MTA2,RBBP4,RBBP7
Protein Size: 593 - Molecular Weight
- 65 kDa
- Gene ID
- 57459
- NCBI Accession
- NM_020699, NP_065750
- UniProt
- Q8WXI9
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