G Elongation Factor, Mitochondrial 2 (GFM2) (C-Term) Peptide
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- Target See all GFM2 products
- GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TVGLKHTATG DTIVSSKSSA LAAARRAERE GEKKHRQNNE AERLLLAGVE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GFM2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))
- Synonyms
- RGD1309854 Peptide, 6530419G12Rik Peptide, A930009M04Rik Peptide, EF-G2mt Peptide, EFG2 Peptide, MST027 Peptide, RRF2mt Peptide, mEF-G 2 Peptide, si:dkey-35i22.3 Peptide, zgc:153835 Peptide, MRRF2 Peptide, RRF2 Peptide, hEFG2 Peptide, ST15 Peptide, G elongation factor, mitochondrial 2 Peptide, G elongation factor mitochondrial 2 Peptide, ribosome-releasing factor 2, mitochondrial Peptide, reversion inducing cysteine rich protein with kazal motifs Peptide, Gfm2 Peptide, GFM2 Peptide, gfm2 Peptide, LOC662021 Peptide, RECK Peptide
- Background
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Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. GFM2 is one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.
Alias Symbols: EFG2, MRRF2, MST027, RRF2, RRF2mt, hEFG2, EF-G2mt, mEF-G 2
Protein Size: 779 - Molecular Weight
- 86 kDa
- Gene ID
- 84340
- NCBI Accession
- NM_032380, NP_115756
- UniProt
- Q969S9
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