General Transcription Factor III (GTF2I) Peptide
GTF2I
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all GTF2I products
- GTF2I (General Transcription Factor III (GTF2I))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GTF2I antibody (Catalog #: ARP31910_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GTF2I (General Transcription Factor III (GTF2I))
- Synonyms
- BAP135 Peptide, BTKAP1 Peptide, DIWS Peptide, GTFII-I Peptide, IB291 Peptide, SPIN Peptide, TFII-I Peptide, WBS Peptide, WBSCR6 Peptide, Gtf2ird1 Peptide, 6030441I21Rik Peptide, BAP-135 Peptide, GtfII-I Peptide, Spin Peptide, bap-135 Peptide, bap135 Peptide, btkap1 Peptide, diws Peptide, gtfii-i Peptide, ib291 Peptide, spin Peptide, tfii-i Peptide, wbs Peptide, wbscr6 Peptide, gtf2i Peptide, gtf2i.L Peptide, general transcription factor IIi Peptide, general transcription factor II I Peptide, general transcription factor IIi S homeolog Peptide, GTF2I Peptide, Gtf2i Peptide, gtf2i Peptide, gtf2i.S Peptide
- Background
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GTF2I is a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon(s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants.
Alias Symbols: WBS, DIWS, SPIN, IB291, BAP135, BTKAP1, TFII-I, WBSCR6, GTFII-I
Protein Interaction Partner: ATF6,BTK,GTF2I,HDAC3,JAK2,MAPK3,MYC,NFKB2,PIAS2,PRKG1,PRRX1,SMAD2,SRC,SRF,STAT1,STAT3,USF1,YY1,ZBTB17,ATF6,BTK,HDAC1,HDAC2,HDAC3,HDAC3,KDM1A,MAPK3,MEPCE,MYC,NAA38,NFI1,OTUB2,PHF21A,PRKG1,PRRX1,PTP4A3,Pias2,SRF,STAT1,STAT3,STX7,SUZ12,USF1,USP7
Protein Size: 978 - Molecular Weight
- 110 kDa
- Gene ID
- 2969
- NCBI Accession
- NM_033000, NP_127493
- UniProt
- Q75M86
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