Heart and Neural Crest Derivatives Expressed 2 (HAND2) (C-Term) Peptide
HAND2
Reactivity: Mouse
Host: Synthetic
BP, WB
-
- Target See all HAND2 products
- HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))
- Protein Region
- C-Term
- Origin
- Mouse
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DQNGEAEAFK AEIKKTDVKE EKRKKELNEI LKSTVSSNDK KTKGRTGWPQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Hand2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))
- Synonyms
- DHAND2 Peptide, Hed Peptide, Thing2 Peptide, bHLHa26 Peptide, dHand Peptide, dhand2 Peptide, hand2 Peptide, xhand2 Peptide, hand2-b Peptide, Hand2' Peptide, dHAND Peptide, HAND2 Peptide, hed Peptide, dhand Peptide, thing2 Peptide, LOC100218345 Peptide, AI225906 Peptide, AI661148 Peptide, Ehand2 Peptide, Th2 Peptide, zdHAND Peptide, zgc:103415 Peptide, Hand2 Peptide, heart and neural crest derivatives expressed 2 Peptide, heart and neural crest derivatives expressed 2 L homeolog Peptide, heart and neural crest derivatives expressed 2 S homeolog Peptide, HAND2 Peptide, Hand2 Peptide, hand2.L Peptide, hand2.S Peptide, hand2 Peptide
- Background
-
Hand2 is essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. It is required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. It plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Hand2 is involved in the development of branchial arches, which give rise to unique structures in the head and neck.
Alias Symbols: AI225906, AI661148, Ehand2, Hed, Th2, Thing2, bHLHa26, dHAND
Protein Interaction Partner: Hand1,Twist1
Protein Size: 217 - Molecular Weight
- 24 kDa
- Gene ID
- 15111
- NCBI Accession
- NM_010402, NP_034532
- UniProt
- Q61039
-
You are here:
