Histone Deacetylase 3 (HDAC3) (C-Term) Peptide
HDAC3
Reactivity: Rat
Host: Synthetic
BP, WB
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- Target See all HDAC3 products
- HDAC3 (Histone Deacetylase 3 (HDAC3))
- Protein Region
- C-Term
- Origin
- Rat
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DVPADLLTYD RTDEADAEER GPEENYSRPE APNEFYDGDH DNDKESDVEI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Hdac3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HDAC3 (Histone Deacetylase 3 (HDAC3))
- Synonyms
- CG2128 Peptide, DHDAC3 Peptide, DmHDAC3 Peptide, Dmel\\CG2128 Peptide, Dromel_CG2128_FBtr0078767_hdac3_mORF Peptide, HDAC Peptide, HDAC3 Peptide, Hdac 3 Peptide, dHDAC3 Peptide, dmHDA402 Peptide, hdac3 Peptide, HDm Peptide, hd3 Peptide, RPD3 Peptide, XRpd3 Peptide, rpd3-2 Peptide, HD3 Peptide, RPD3-2 Peptide, AW537363 Peptide, zgc:55927 Peptide, Histone deacetylase 3 Peptide, histone deacetylase 3 Peptide, histone deacetylase 3 S homeolog Peptide, HDAC3 Peptide, hdac3 Peptide, CNL05260 Peptide, Hdac3 Peptide, hdac3.S Peptide
- Background
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Hdac3 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Hdac3 is required to repress transcription of the POU1F1 transcription factor. Hdac3 acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.
Alias Symbols: Hdac3
Protein Interaction Partner: Hr
Protein Size: 428 - Molecular Weight
- 49 kDa
- Gene ID
- 84578
- NCBI Accession
- NM_053448, NP_445900
- UniProt
- Q6P6W3
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