Histone Deacetylase 8 (HDAC8) (N-Term) Peptide
HDAC8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HDAC8 products
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HDAC8 antibody (Catalog #: ARP34586_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- Synonyms
- HD8 Peptide, CDLS5 Peptide, HDACL1 Peptide, MRXS6 Peptide, RPD3 Peptide, WTS Peptide, 2610007D20Rik Peptide, RGD1562895 Peptide, wu:fd19a02 Peptide, zgc:66196 Peptide, ATHDA8 Peptide, HDA8 Peptide, HISTONE DEACETYLASE 8 Peptide, T27G7.14 Peptide, T27G7_14 Peptide, histone deacetylase 8 Peptide, histone deacetylase 8 Peptide, histone deacetylase 8 L homeolog Peptide, CC1G_05302 Peptide, hdac8 Peptide, HDAC8 Peptide, Hdac8 Peptide, hdac8.L Peptide, HDA08 Peptide
- Background
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HDACL1, RPD3, HD8, CDA07
Protein Interaction Partner: HIST2H4A,HIST3H3,PRKACA,RUNX1T1,CBFA2T3,MDC1,RUNX1T1
Protein Size: 377 - Molecular Weight
- 42 kDa
- Gene ID
- 55869
- NCBI Accession
- NM_018486, NP_060956
- UniProt
- Q9BY41
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