Hypermethylated in Cancer 1 (HIC1) (Middle Region) Peptide
HIC1
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all HIC1 products
- HIC1 (Hypermethylated in Cancer 1 (HIC1))
- Protein Region
- Middle Region
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HIC1 antibody (Catalog #: ARP38806_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HIC1 (Hypermethylated in Cancer 1 (HIC1))
- Synonyms
- zfHIC1 Peptide, HIC1 Peptide, ZBTB29 Peptide, ZNF901 Peptide, hic-1 Peptide, AA408311 Peptide, HIC-1 Peptide, hypermethylated in cancer 1 Peptide, HIC ZBTB transcriptional repressor 1 Peptide, hic1 Peptide, HIC1 Peptide, Hic1 Peptide
- Background
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HIC1 is a transcriptional repressor. HIC1 may act as a tumor suppressor. HIC1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIC1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney.
Alias Symbols: ZBTB29, hic-1, ZNF901
Protein Interaction Partner: CTBP1,HDAC1,HIC1,SIRT1,Ctbp1,HIC1
Protein Size: 714 - Molecular Weight
- 74 kDa
- Gene ID
- 3090
- NCBI Accession
- NM_006497, NP_006488
- UniProt
- Q14526
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