High Mobility Group Nucleosome Binding Domain 1 (HMGN1) (Middle Region) Peptide
HMGN1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all HMGN1 products
- HMGN1 (High Mobility Group Nucleosome Binding Domain 1 (HMGN1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HMGN1 antibody (Catalog #: ARP32627_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HMGN1 (High Mobility Group Nucleosome Binding Domain 1 (HMGN1))
- Synonyms
- HMG14 Peptide, hmg14 Peptide, hmgn1 Peptide, hmgn1b Peptide, HMG-14 Peptide, Hmg14 Peptide, high mobility group nucleosome binding domain 1 Peptide, high mobility group nucleosome binding domain 1 S homeolog Peptide, high mobility group nucleosomal binding domain 1 Peptide, non-histone chromosomal protein HMG-14 Peptide, HMGN1 Peptide, hmgn1.S Peptide, hmgn1 Peptide, Hmgn1 Peptide, LOC785479 Peptide
- Background
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Chromosomal protein HMG14 (HMGN1) and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ27265, FLJ31471, HMG14, MGC104230, MGC117425
Protein Interaction Partner: EP300,HMGN1,HMGN2,IRF2,PRKACA,PRKCA,RPS6KA3,RPS6KA4,RPS6KA5,YWHAZ,HMGN1,YWHAZ
Protein Size: 100 - Molecular Weight
- 11 kDa
- Gene ID
- 3150
- NCBI Accession
- NM_004965, NP_004956
- UniProt
- P05114
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