Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11) (Middle Region) Peptide
HSD17B11
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all HSD17B11 products
- HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))
- Protein Region
- Middle Region
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- IYSAAKKVKE EVGDVSILVN NAGVVYTADL FATQDPQIEK TFEVNVLAHF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Hsd17b11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))
- Synonyms
- 17BHSD11 Peptide, DHRS8 Peptide, PAN1B Peptide, RETSDR2 Peptide, SDR16C2 Peptide, Dhrs8 Peptide, HSD17B13 Peptide, MGC84756 Peptide, HSD17B11 Peptide, Pan1b Peptide, SDR2 Peptide, retSDR2 Peptide, 17-beta-HSD 11 Peptide, 17-beta-HSD XI Peptide, 17bHSD11 Peptide, 17betaHSD11 Peptide, 17betaHSDXI Peptide, hydroxysteroid 17-beta dehydrogenase 11 Peptide, hydroxysteroid (17-beta) dehydrogenase 11 Peptide, hydroxysteroid (17-beta) dehydrogenase 11 L homeolog Peptide, estradiol 17-beta-dehydrogenase 11 Peptide, HSD17B11 Peptide, Hsd17b11 Peptide, hsd17b11.L Peptide, hsd17b11 Peptide, LOC100348005 Peptide, LOC100520923 Peptide
- Background
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Hsd17b11 can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. Hsd17b11 may act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. It has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione.
Alias Symbols: Dhrs8, Pan1b, SDR2, retSDR2
Protein Size: 298 - Molecular Weight
- 33 kDa
- Gene ID
- 114664
- NCBI Accession
- NM_053262, NP_444492
- UniProt
- Q9EQ06
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