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Heat Shock 70kDa Protein 4 (HSPA4) (Middle Region) Peptide

HSPA4 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN978305
  • Target See all HSPA4 products
    HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-HSPA4 antibody (Catalog #: ARP46074_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))
    Synonyms
    APG-2 Peptide, HS24/P52 Peptide, HSPH2 Peptide, RY Peptide, hsp70 Peptide, hsp70RY Peptide, Hsp110 Peptide, Hsp70 Peptide, irp94 Peptide, 70kDa Peptide, AI317151 Peptide, Hsp70RY Peptide, mKIAA4025 Peptide, hspa4 Peptide, wu:fi30e11 Peptide, zgc:55743 Peptide, zgc:77413 Peptide, hs24/p52 Peptide, hspa4-a Peptide, osp94 Peptide, pg-2 Peptide, hspa4l Peptide, wu:fc41d05 Peptide, wu:fi59h02 Peptide, wu:fj35c08 Peptide, zgc:55506 Peptide, heat shock protein family A (Hsp70) member 4 Peptide, heat shock protein family A member 4 Peptide, heat shock protein 4 Peptide, heat shock protein 4b Peptide, heat shock protein family A (Hsp70) member 4 S homeolog Peptide, heat shock protein 4a Peptide, HSPA4 Peptide, Hspa4 Peptide, hspa4b Peptide, hspa4.S Peptide, hspa4a Peptide
    Background
    HSPA4(Hsp70) belongs to the heat shock protein 70 family. It was isolated as a putative Rictor interacting protein and interaction with membranes acts as a platform for its release into the extracellular environment during its recovery from stress. Hsp70 gene expression in Rheumatoid Arthitis-affected synovial tissue is followed by Hsp70 cell surface expression on fibroblast-like synovial cells growing from RA synovial tissue. Serum Hsp70 levels were increased in Systemic sclerosis patients, and associated with pulmonary fibrosis, skin sclerosis, renal vascular damage, oxidative stress, and inflammation.

    Alias Symbols: APG-2, HS24/P52, MGC131852, RY, hsp70, hsp70RY, HSPH2

    Protein Interaction Partner: KPNA2,BRMS1,CD40,CDC73,DDIT4,DUSP1,ESR1,GATA1,GRPEL2,HDAC3,IKBKG,KPNA2,NR3C2,OLR1,PHLDA1,PPP1CA,PRSS23,RAF1,SMAD3,STUB1,TRAF6,APAF1,BAG1,BAG1,BAG4,BAG5,BCOR,Bmi1,CDC73,CDK1,CHTF18,Cbx2,DNAJB1,DNAJB11,DNAJC3,DNMBP,ESR1,FES,GUCY1A2,H2AFY,HCFC1,HDAC1,HDAC2,HDAC3,HNRNPD,HSBP1,HSF1,HSPBP1,HTT,IRS4,ISG15,KRT18,LIMK1,MAP3K3,MARK4,NCOR1,NQO1,P2rx7,PARK2,PCGF1,PRKCB,PRSS23,SELS,SGTA,SSE1,STIP1,STUB1,TCERG1,TIMM44,TP53,TTC1,UBC,ZMYM2

    Protein Size: 840
    Molecular Weight
    94 kDa
    Gene ID
    3308
    NCBI Accession
    NM_002154, NP_002145
    UniProt
    P34932
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