Isoleucyl-tRNA Synthetase (IARS) (Middle Region) Peptide
IARS
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all IARS products
- IARS (Isoleucyl-tRNA Synthetase (IARS))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- YEAAKVFGLR SRKLKLFLNE TQTQEITEDI PVKTLNMKTV YVSVLPTTAD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IARS Antibody(ARP54954_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IARS (Isoleucyl-tRNA Synthetase (IARS))
- Synonyms
- fi46h05 Peptide, zgc:63790 Peptide, wu:fi46h05 Peptide, K19E20.18 Peptide, K19E20_18 Peptide, ovule abortion 2 Peptide, ECK0027 Peptide, ilvS Peptide, JW0024 Peptide, An08g06770 Peptide, AO090012000505 Peptide, 2510016L12Rik Peptide, AI327140 Peptide, AU044614 Peptide, E430001P04Rik Peptide, ILRS Peptide, Iarsl Peptide, IARS1 Peptide, ILERS Peptide, IRS Peptide, PRO0785 Peptide, isoleucyl-tRNA synthetase Peptide, tRNA synthetase class I (I, L, M and V) family protein Peptide, isoleucine--tRNA ligase Peptide, isoleucyl-tRNA synthetase, cytoplasmic Peptide, isoleucine-tRNA synthetase Peptide, iars Peptide, IARS Peptide, OVA2 Peptide, ileS Peptide, MBAR_RS19160 Peptide, Rmag_0340 Peptide, ANI_1_964074 Peptide, CHLREDRAFT_106327 Peptide, EDI_049880 Peptide, OE_RS08520 Peptide, AOR_1_1912194 Peptide, Iars Peptide
- Background
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Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
Alias Symbols: FLJ20736, IARS1, ILRS, PRO0785, IRS, ILERS
Protein Interaction Partner: AR,EPRS,GARS,AIMP2,AKTIP,BCAR3,EPRS,GARS,GSTK1,MAGED1,MCC,SGK1,SNCA,TRAF6,TSC22D1,USP19,VHL
Protein Size: 1262 - Molecular Weight
- 144 kDa
- Gene ID
- 3376
- NCBI Accession
- NM_013417, NP_038203
- UniProt
- P41252
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