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Interleukin 11 Receptor, alpha (IL11RA) (N-Term) Peptide

IL11RA Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN978471
  • Target See all IL11RA products
    IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-IL11RA antibody (Catalog #: ARP46466_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
    Synonyms
    CRSDA Peptide, fi26e06 Peptide, il-11ra Peptide, wu:fi26e06 Peptide, AI314697 Peptide, GP130 Peptide, Il-11ra Peptide, Il11ra Peptide, Il11ra2 Peptide, NR1 Peptide, interleukin 11 receptor subunit alpha Peptide, interleukin 11 receptor, alpha Peptide, interleukin 11 receptor subunit alpha 1 Peptide, interleukin 11 receptor, alpha chain 1 Peptide, IL11RA Peptide, il11ra Peptide, Il11ra1 Peptide, Il11ra Peptide
    Background
    Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. IL11RA is the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain.Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.

    Alias Symbols: MGC2146, CRSDA

    Protein Interaction Partner: IL11

    Protein Size: 422
    Molecular Weight
    43 kDa
    Gene ID
    3590
    NCBI Accession
    NM_004512, NP_004503
    UniProt
    Q14626
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