Interleukin 1 Receptor, Type I (IL1R1) (C-Term) Peptide
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- Target See all IL1R1 products
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- Protein Region
- C-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LELEKIQDYE KMPESIKFIK QKHGAIRWSG DFTQGPQSAK TRFWKNVRYH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IL1R1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- Synonyms
- CD121A Peptide, D2S1473 Peptide, IL-1R-alpha Peptide, IL1R Peptide, IL1RA Peptide, P80 Peptide, CD121a Peptide, CD121b Peptide, IL-iR Peptide, Il1r-1 Peptide, DER4 Peptide, Fit-1 Peptide, Ly84 Peptide, ST2L Peptide, St2 Peptide, St2-rs1 Peptide, T1 Peptide, T1/ST2 Peptide, interleukin 1 receptor type 1 Peptide, interleukin 1 receptor, type I Peptide, interleukin 1 receptor-like 1 Peptide, IL1R1 Peptide, Il1r1 Peptide, Il1rl1 Peptide
- Background
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The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
Alias Symbols: CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80
Protein Interaction Partner: TICAM2,IL1A,IL1B,IL1F10,IL1RAP,IL1RN,IRAK2,MYD88,PIK3R1,SIGIRR,TICAM2,TOLLIP,IL1B,IL1RAP,IL1RN,IRAK2,MYD88,PIK3R1,SIGIRR,TOLLIP,TOM1,UBC
Protein Size: 569 - Molecular Weight
- 63 kDa
- Gene ID
- 3554
- NCBI Accession
- NM_000877, NP_000868
- UniProt
- P14778
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