Interleukin 2 Receptor, beta (IL2RB) (C-Term) Peptide
IL2RB
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all IL2 Receptor beta (IL2RB) products
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- QGYFFFHLPD ALEIEACQVY FTYDPYSEED PDEGVAGAPT GSSPQPLQPL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IL2RB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- Synonyms
- IL2RB Peptide, il-2rb Peptide, CD122 Peptide, IL15RB Peptide, P70-75 Peptide, IL2RBC Peptide, IL-15Rbeta Peptide, IL15Rbeta Peptide, Il-2/15Rbeta Peptide, Il-2Rbeta Peptide, p70 Peptide, interleukin 2 receptor subunit beta Peptide, interleukin-2 receptor subunit beta Peptide, interleukin 2 receptor, beta Peptide, interleukin 2 receptor, beta chain Peptide, IL2RB Peptide, LOC510185 Peptide, il2rb Peptide, Il2rb Peptide
- Background
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The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
Alias Symbols: CD122, P70-75, IL15RB
Protein Interaction Partner: GNB2L1,IL2,JAK1,CISH,EIF3B,FYN,GNB2L1,GRB2,IL15,IL15RA,IL2,IL2RA,IL2RG,JAK1,JAK3,LCK,LYN,PIK3R1,PTPN6,RAF1,SHB,SHC1,SOCS1,SOCS3,STAT1,STAT3,STAT5A,STAT5B,SYK,CISH,GNB2L1,GRB2,HGS,JAK1,JAK2,SHB,SHC1,SOCS1,STAT1,STAT3,STAT5A,STAT5B,UBC
Protein Size: 551 - Molecular Weight
- 58 kDa
- Gene ID
- 3560
- NCBI Accession
- NM_000878, NP_000869
- UniProt
- P14784
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