Interleukin 4 (IL4) Peptide
IL4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all IL-4 (IL4) products
- IL-4 (IL4) (Interleukin 4 (IL4))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IL4 antibody (Catalog #: ARP54329_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IL-4 (IL4) (Interleukin 4 (IL4))
- Synonyms
- IL4 Peptide, IL-4 Peptide, BCGF-1 Peptide, BCGF1 Peptide, BSF-1 Peptide, BSF1 Peptide, Il-4 Peptide, Il4e12 Peptide, IL2 Peptide, interleukin 4 Peptide, IL4 Peptide, Il4 Peptide
- Background
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IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Alias Symbols: BSF1, IL-4, MGC79402, BCGF1, BSF-1, BCGF-1
Protein Interaction Partner: IL2RG,IL4R,IL4R,CD53,IL13RA2,IL2RG,IL4R,PIK3CD,A2M,IL4R
Protein Size: 153 - Molecular Weight
- 15 kDa
- Gene ID
- 3565
- NCBI Accession
- NM_000589, NP_000580
- UniProt
- P05112
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