Interleukin 5 Receptor, alpha (IL5RA) (N-Term) Peptide
IL5RA
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all IL5RA products
- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GLAQVLLQWK PNPDQEQRNV NLEYQVKINA PKEDDYETRI TESKCVTILH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IL5RA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
- Synonyms
- MGC86517 Peptide, IL5RA Peptide, il5r Peptide, cdw125 Peptide, hsil5r3 Peptide, gpIL-5ra Peptide, CD125 Peptide, CDw125 Peptide, HSIL5R3 Peptide, IL5R Peptide, Il5r Peptide, interleukin 5 receptor subunit alpha L homeolog Peptide, interleukin 5 receptor subunit alpha Peptide, interleukin 5 receptor, alpha Peptide, il5ra.L Peptide, IL5RA Peptide, il5ra Peptide, Il5ra Peptide
- Background
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The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
Alias Symbols: CD125, CDw125, HSIL5R3, IL5R, MGC26560
Protein Size: 420 - Molecular Weight
- 46 kDa
- Gene ID
- 3568
- NCBI Accession
- NM_175726, NP_783853
- UniProt
- Q01344
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