Inositol-Tetrakisphosphate 1-Kinase (ITPK1) (N-Term) Peptide
ITPK1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ITPK1 products
- ITPK1 (Inositol-Tetrakisphosphate 1-Kinase (ITPK1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ITPK1 antibody (Catalog #: ARP54993_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ITPK1 (Inositol-Tetrakisphosphate 1-Kinase (ITPK1))
- Synonyms
- ITRPK1 Peptide, BC031182 Peptide, wu:fj15d08 Peptide, zgc:56075 Peptide, inositol-tetrakisphosphate 1-kinase Peptide, inositol 1,3,4-triphosphate 5/6 kinase Peptide, inositol-tetrakisphosphate 1-kinase L homeolog Peptide, inositol-tetrakisphosphate 1-kinase a Peptide, ITPK1 Peptide, Itpk1 Peptide, itpk1.L Peptide, itpk1a Peptide
- Background
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ITPK1 is the kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. It may also act as an isomerase that interconverts the inositol tetraphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. It probably acts as the rate-limiting enzyme of the InsP6 pathway. ITPK1 modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.
Alias Symbols: ITRPK1
Protein Interaction Partner: COPS8,GPS1,TRAF2,TRAF2
Protein Size: 414 - Molecular Weight
- 45 kDa
- Gene ID
- 3705
- NCBI Accession
- NM_014216, NP_055031
- UniProt
- Q13572
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