KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) Peptide
KHDRBS1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all KHDRBS1 products
- KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KHDRBS1 antibody (Catalog #: ARP40665_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))
- Synonyms
- Sam68 Peptide, p62 Peptide, p68 Peptide, fj90g10 Peptide, khdrbs1 Peptide, wu:fa18g12 Peptide, wu:fa56c01 Peptide, wu:fc91b01 Peptide, wu:fj90g10 Peptide, zgc:113899 Peptide, KHDRBS1 Peptide, P62 Peptide, khdrbs1l Peptide, sb:cb97 Peptide, wu:fb07d11 Peptide, wu:fi43c05 Peptide, zgc:85948 Peptide, KH RNA binding domain containing, signal transduction associated 1 Peptide, KH domain containing, RNA binding, signal transduction associated 1a Peptide, KH domain containing, RNA binding, signal transduction associated 1 Peptide, KH domain containing, RNA binding, signal transduction associated 1 S homeolog Peptide, KH domain containing, RNA binding, signal transduction associated 1b Peptide, KHDRBS1 Peptide, khdrbs1a Peptide, khdrbs1 Peptide, Khdrbs1 Peptide, khdrbs1.S Peptide, khdrbs1b Peptide
- Background
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KHDRBS1 recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, KHDRBS1 functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. KHDRBS1 play a role in G2-M progression in the cell cycle. It represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. KHDRBS1 also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.
Alias Symbols: FLJ34027, Sam68, p62, p68
Protein Interaction Partner: GRAP2,GRB2,HCK,HNRNPK,HNRNPK,LCK,PIK3R1,RASA1,SRC,src,BTK,CBL,CDK1,CREBBP,DHX9,EMG1,FNBP4,FYN,GRAP,GRAP2,GRB2,HCK,HNRNPK,INSR,ITK,JAK3,KHDRBS1,KHDRBS3,LCK,LYN,MAPK1,NCF1,NCK1,PIK3R1,PLCG1,PLCG2,PRMT1,PTK6,PTPN6,RAPSN,RASA1,SMAD2,SMARCA2,SRC,STAT3,STUB1,TUBB3,UBA52,WBP4,YTHDC1,BTK,CREBBP,CRK,DHX9,EMG1,FNBP4,FYN,GRAP2,GRB2,Grap2,HNRNPK,INSR,IRS1,ITK,KHDRBS1,KHDRBS2,Khdrbs3,LCK,NCF1,NCK1,PACSIN1,PACSIN2,PACSIN3,PIK3R1,PLCG1,PRMT1,PTK6,RAPSN,RASA1,SRC,STAT3,STUB1,TNFSF11,TUBB3,WBP4,YTHDC1
Protein Size: 443 - Molecular Weight
- 48 kDa
- Gene ID
- 10657
- NCBI Accession
- NM_006559, NP_006550
- UniProt
- Q07666
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