Kelch-Like 12 (Drosophila) (KLHL12) (N-Term) Peptide
KLHL12
Reactivity: Rat
Host: Synthetic
BP, WB
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- Target See all KLHL12 products
- KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
- Protein Region
- N-Term
- Origin
- Rat
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DIMTNTHAKS ILNSMNSLRK SNTLCDVTLR VEQKDFPAHR IVLAACSDYF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Klhl12 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
- Synonyms
- zgc:92570 Peptide, wu:fi60g03 Peptide, C3ip1 Peptide, C3IP1 Peptide, DKIR Peptide, hDKIR Peptide, Ski2 like RNA helicase Peptide, kelch like family member 12 L homeolog Peptide, kelch like family member 12 Peptide, kelch-like family member 12 Peptide, kelch-like 12 Peptide, SKIV2L Peptide, klhl12.L Peptide, KLHL12 Peptide, klhl12 Peptide, Klhl12 Peptide
- Background
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Klhl12 serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. It negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
Alias Symbols: C3ip1, MGC93127
Protein Size: 568 - Molecular Weight
- 62 kDa
- Gene ID
- 266772
- NCBI Accession
- NM_153730, NP_714952
- UniProt
- Q8R2H4
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