Kelch-Like 3 (KLHL3) (N-Term) Peptide
KLHL3
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all KLHL3 products
- KLHL3 (Kelch-Like 3 (KLHL3))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KLHL3 antibody (Catalog #: ARP34561_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KLHL3 (Kelch-Like 3 (KLHL3))
- Synonyms
- 7530408C15Rik Peptide, AI430941 Peptide, EG627648 Peptide, PHA2D Peptide, RGD1565218 Peptide, kelch like family member 3 Peptide, kelch-like 3 Peptide, kelch-like family member 3 Peptide, KLHL3 Peptide, Klhl3 Peptide
- Background
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KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77 % similarity with Drosophila kelch and 89 % similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q, however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
Alias Symbols: FLJ40871, KIAA1129, MGC44594, PHA2D
Protein Interaction Partner: GNAI1,GNAO1,OPRD1,SYNCRIP,SYT2
Protein Size: 587 - Molecular Weight
- 65 kDa
- Gene ID
- 26249
- NCBI Accession
- NM_017415, NP_059111
- UniProt
- Q9UH77
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