Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) Peptide
KREMEN1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all KREMEN1 products
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KREMEN1 antibody (Catalog #: ARP44880_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
- Synonyms
- KREMEN1 Peptide, krm1 Peptide, kremen Peptide, kremem1 Peptide, KREMEN Peptide, KRM1 Peptide, AV002070 Peptide, Kremen Peptide, Krm1 Peptide, si:ct737139.1 Peptide, si:dkeyp-7c9.1 Peptide, kringle containing transmembrane protein 1 Peptide, kringle containing transmembrane protein 1 S homeolog Peptide, KREMEN1 Peptide, kremen1 Peptide, Kremen1 Peptide, kremen1.S Peptide
- Background
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KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. It is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Alias Symbols: FLJ31863, KREMEM1, KREMEN, KRM1
Protein Interaction Partner: DKK1
Protein Size: 475 - Molecular Weight
- 50 kDa
- Gene ID
- 83999
- NCBI Accession
- NM_001039570, NP_001034659
- UniProt
- Q96MU8
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