Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1) (N-Term) Peptide
LDOC1
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all LDOC1 products
- LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-LDOC1 antibody (Catalog #: ARP38983_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))
- Synonyms
- BCUR1 Peptide, Mar7 Peptide, Mart7 Peptide, RGD1565644 Peptide, Gm366 Peptide, LDOC1 Peptide, LDOC1, regulator of NFKB signaling Peptide, regulator of NFKB signaling Peptide, LDOC1 Peptide, Ldoc1 Peptide
- Background
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LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.
Alias Symbols: BCUR1, Mar7, Mart7
Protein Interaction Partner: CEBPE,MZF1,AATF,ABLIM1,AEBP2,AP1M1,ATF4,C10orf18,CCDC85B,CEBPE,DPPA4,FAM107A,FAM193B,FOSL1,FXR2,GNL3L,HGS,IKZF5,KRT15,KRT18,LNX1,MZF1,NRIP1,POLL,SMARCD1,UTP14A,ZBTB16,ZNF250,ZNF408,AATF,ABLIM1,AEBP2,AP1M1,ATF4,C10orf18,CCDC85B,DPPA4,FAM107A,FAM193B,FOSL1,FXR2,GNL3L,HGS,IKZF5,KRT15,KRT18,LNX1,NRIP1,POLL,SMARCD1,UTP14A,ZBTB16,ZNF250,ZNF408
Protein Size: 146 - Molecular Weight
- 17 kDa
- Gene ID
- 23641
- NCBI Accession
- NM_012317, NP_036449
- UniProt
- O95751
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