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LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) Peptide

LFNG Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN979277
  • Target See all LFNG products
    LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-LFNG antibody (Catalog #: ARP44923_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))
    Synonyms
    SCDO3 Peptide, AW061165 Peptide, id:ibd2614 Peptide, id:ibd5029 Peptide, id:ibd5138 Peptide, l-fng Peptide, wu:fc69h02 Peptide, wu:fi34c01 Peptide, LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Peptide, LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase S homeolog Peptide, LFNG Peptide, Lfng Peptide, lfng.S Peptide, lfng Peptide
    Background
    LFNG is a member of the glycosyltransferase superfamily. It is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in the gene that encodes this protein have been associated with autosomal recessive spondylocostal dysostosis 3. This gene encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Alternatively spliced transcript variants that encode different isoforms have been described, however, not all variants have been fully characterized.

    Alias Symbols: SCDO3

    Protein Interaction Partner: NOTCH1,NOTCH2

    Protein Size: 361
    Molecular Weight
    39 kDa
    Gene ID
    3955
    NCBI Accession
    NM_001040168, NP_001035258
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