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Lamin B2 (LMNB2) Peptide

LMNB2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN979359
  • Target See all Lamin B2 (LMNB2) products
    Lamin B2 (LMNB2)
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-LMNB2 antibody (Catalog #: ARP46356_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Lamin B2 (LMNB2)
    Synonyms
    lmnb2-a Peptide, LMNB2 Peptide, lmn2 Peptide, lamb2 Peptide, Lamin-L(II) Peptide, LOC100136040 Peptide, im:7142331 Peptide, lamin Peptide, wu:fb94e05 Peptide, wu:fb95e12 Peptide, wu:fc15d06 Peptide, wu:fc49h03 Peptide, lamin-b2 Peptide, lmnb2 Peptide, LAMB2 Peptide, LMN2 Peptide, RGD1563803 Peptide, lamin B2 S homeolog Peptide, lamin B2 Peptide, lamin B2 L homeolog Peptide, lmnb2.S Peptide, LMNB2 Peptide, lmnb2 Peptide, lmnb2.L Peptide, Lmnb2 Peptide
    Background
    The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. LMNB2 is one of the two B type proteins, B2.The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B2. This gene is in a head-to-tail orientation with the gene for the translocase of inner mitochondrial membrane 13 homolog gene.

    Alias Symbols: LAMB2, LMN2, MGC2721

    Protein Interaction Partner: ORC2L,XRCC5,LMNB2,PRKCD,TMPO

    Protein Size: 600
    Molecular Weight
    68 kDa
    Gene ID
    84823
    NCBI Accession
    NM_032737, NP_116126
    UniProt
    Q03252
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