P53-Induced Death Domain Protein (PIDD) (Middle Region) Peptide
PIDD
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PIDD products
- PIDD (P53-Induced Death Domain Protein (PIDD))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RRDPEQVLLQ CLPRNKVDAT LRRLLERYRG PEPSDTVEMF EGEEFFAAFE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-LRDD Antibody(ARP57270_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PIDD (P53-Induced Death Domain Protein (PIDD))
- Synonyms
- 1200011D09Rik Peptide, AU042446 Peptide, Pidd Peptide, LRDD Peptide, Lrdd Peptide, p53 induced death domain protein 1 Peptide, p53-induced death domain protein 1 Peptide, Pidd1 Peptide, PIDD1 Peptide
- Background
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The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: DKFZp434D229, MGC16925, PIDD, LRDD
Protein Interaction Partner: CRADD,CASP2,CCDC85B,CRADD,EFEMP2,FADD,MADD,MDFI,CASP2,CCDC85B,CRADD,EFEMP2,FADD,IKBKG,MADD,MDFI,RIPK1
Protein Size: 753 - Molecular Weight
- 83 kDa
- Gene ID
- 55367
- NCBI Accession
- NM_018494, NP_060964
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