Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (N-Term) Peptide
LTB
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all LTB products
- LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AVPITVLAVL ALVPQDQGGL VTETADPGAQ AQQGLGFQKL PEEEPETDLS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-LTB Antibody(ARP45280_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
- Synonyms
- AI662801 Peptide, LTbeta Peptide, Tnfc Peptide, Tnfsf3 Peptide, p33 Peptide, TNFC Peptide, TNFSF3 Peptide, LT-b Peptide, LT-beta Peptide, TNF-C Peptide, lymphotoxin B Peptide, lymphotoxin beta Peptide, Ltb Peptide, LTB Peptide
- Background
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Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: TNFC, TNFSF3, p33
Protein Interaction Partner: LTA,LTB,LTBR,TNFRSF1A,TNFSF14,LTA,TNFRSF1A
Protein Size: 244 - Molecular Weight
- 25 kDa
- Gene ID
- 4050
- NCBI Accession
- NM_002341, NP_002332
- UniProt
- Q06643
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