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Lysocardiolipin Acyltransferase 1 (LCLAT1) (Middle Region) Peptide

LCLAT1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN979661
  • Target See all LCLAT1 products
    LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-LYCAT antibody (Catalog #: ARP44426_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))
    Synonyms
    lclat1 Peptide, zgc:77380 Peptide, wu:fj17g04 Peptide, LYCAT Peptide, lycat Peptide, agpat8 Peptide, alcat1 Peptide, 1agpat8 Peptide, AGPATP8 Peptide, 1AGPAT8 Peptide, AGPAT8 Peptide, ALCAT1 Peptide, HSRG1849 Peptide, UNQ1849 Peptide, AI181996 Peptide, Agpat8 Peptide, Alcat1 Peptide, Gm91 Peptide, Lycat Peptide, RGD1565906 Peptide, lysocardiolipin acyltransferase 1 Peptide, lclat1 Peptide, LCLAT1 Peptide, Lclat1 Peptide
    Background
    LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.

    Alias Symbols: ALCAT1, FLJ37965, UNQ1849, LYCAT, AGPAT8, 1AGPAT8, HSRG1849

    Protein Size: 376
    Molecular Weight
    44 kDa
    Gene ID
    253558
    NCBI Accession
    NM_001002257, NP_001002257
    UniProt
    Q6UWP7
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