Lysocardiolipin Acyltransferase 1 (LCLAT1) (Middle Region) Peptide
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- Target See all LCLAT1 products
- LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-LYCAT antibody (Catalog #: ARP44426_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))
- Synonyms
- lclat1 Peptide, zgc:77380 Peptide, wu:fj17g04 Peptide, LYCAT Peptide, lycat Peptide, agpat8 Peptide, alcat1 Peptide, 1agpat8 Peptide, AGPATP8 Peptide, 1AGPAT8 Peptide, AGPAT8 Peptide, ALCAT1 Peptide, HSRG1849 Peptide, UNQ1849 Peptide, AI181996 Peptide, Agpat8 Peptide, Alcat1 Peptide, Gm91 Peptide, Lycat Peptide, RGD1565906 Peptide, lysocardiolipin acyltransferase 1 Peptide, lclat1 Peptide, LCLAT1 Peptide, Lclat1 Peptide
- Background
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LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.
Alias Symbols: ALCAT1, FLJ37965, UNQ1849, LYCAT, AGPAT8, 1AGPAT8, HSRG1849
Protein Size: 376 - Molecular Weight
- 44 kDa
- Gene ID
- 253558
- NCBI Accession
- NM_001002257, NP_001002257
- UniProt
- Q6UWP7
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