TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) Peptide
TAB2
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all TAB2 products
- TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAP3K7IP2 antibody (Catalog #: ARP32402_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
- Synonyms
- CHTD2 Peptide, MAP3K7IP2 Peptide, 1110030N06Rik Peptide, A530078N03Rik Peptide, Map3k7ip2 Peptide, mKIAA0733 Peptide, map3k7ip2 Peptide, zgc:77446 Peptide, TGF-beta activated kinase 1/MAP3K7 binding protein 2 Peptide, TAB2 Peptide, Tab2 Peptide, tab2 Peptide
- Background
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MAP3K7IP2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of NF.:B and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serving as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF.:B (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
Alias Symbols: CHTD2, MAP3K7IP2
Protein Interaction Partner: EIF2AK2,HDAC3,IRAK1,MAP3K7,NR2C2,TAB1,TNFRSF11A,TRAF2,TRAF6,XIAP,CD82,CNTN2,CS,HDAC1,HDAC3,HDAC5,IRAK1,MAP3K7,Map3k7,NCOR1,NFKB1,NUMBL,RIPK1,TAB1,TAB2,TAB3,TBL1X,TNFRSF11A,TRAF2,TRAF6,XIAP
Protein Size: 693 - Molecular Weight
- 76 kDa
- Gene ID
- 23118
- NCBI Accession
- NM_015093, NP_055908
- UniProt
- Q9NYJ8
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