Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3) (C-Term) Peptide
MAPKAPK3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MAPKAP Kinase 3 (MAPKAPK3) products
- MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KEEMTSALAT MRVDYDQVKI KDLKTSNNRL LNKRRKKQAG SSSASQGCNN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAPKAPK3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
- Synonyms
- 3PK Peptide, MAPKAP-K3 Peptide, MAPKAP3 Peptide, MAPKAPK-3 Peptide, MK-3 Peptide, AI874665 Peptide, MK3 Peptide, MapkKapk3 Peptide, MAPKAPK3 Peptide, mapkapk3 Peptide, MGC154360 Peptide, 3pk Peptide, mapkap3 Peptide, zgc:158342 Peptide, mitogen-activated protein kinase-activated protein kinase 3 Peptide, mitogen-activated protein kinase-activated protein kinase 3 S homeolog Peptide, MAPKAPK3 Peptide, Mapkapk3 Peptide, mapkapk3.S Peptide, mapkapk3 Peptide
- Background
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MAPKAPK3 is a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
Alias Symbols: 3PK, MAPKAP3, MK-3, MAPKAP-K3, MAPKAPK-3
Protein Interaction Partner: BMI1,CBX4,PHC2,EEF2,EEF2K,HSPB1,MAPK13,MAPK14,TCF3,MAPK14,TCF3,UBC
Protein Size: 382 - Molecular Weight
- 43 kDa
- Gene ID
- 7867
- NCBI Accession
- NM_004635, NP_004626
- UniProt
- Q16644
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