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Mediator Complex Subunit 6 (MED6) (Middle Region) Peptide

MED6 Reactivity: Human Host: Synthetic BP, WB, ChIP
Catalog No. ABIN979954
  • Target See all MED6 products
    MED6 (Mediator Complex Subunit 6 (MED6))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-MED6 antibody (Catalog #: ARP34219_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    MED6 (Mediator Complex Subunit 6 (MED6))
    Synonyms
    NY-REN-28 Peptide, wu:fa14c11 Peptide, zgc:86933 Peptide, 1500012F11Rik Peptide, AU019660 Peptide, AV213303 Peptide, RNA polymerase transcriptional regulation mediator-like protein Peptide, mediator complex subunit 6 Peptide, hypothetical protein Peptide, MED6 Peptide, Med6 Peptide, med6 Peptide, CAALFM_C306170CA Peptide
    Background
    MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

    Alias Symbols: NY-REN-28

    Protein Interaction Partner: PARP1,RARA,MED25,MED8,MED9,PARP1,RARA,SMAD1,SMAD2,CDK8,ESR1,ESR2,MED1,MED10,MED14,MED15,MED19,MED21,MED25,MED26,MED28,MED29,MED30,MED9,THRA,VDR

    Protein Size: 246
    Molecular Weight
    28 kDa
    Gene ID
    10001
    NCBI Accession
    NM_005466, NP_005457
    UniProt
    O75586
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