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Protein AF-9 (MLLT3) Peptide

MLLT3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN980125
  • Target See all AF9 (MLLT3) products
    AF9 (MLLT3) (Protein AF-9 (MLLT3))
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-MLLT3 antibody (Catalog #: ARP38490_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    AF9 (MLLT3) (Protein AF-9 (MLLT3))
    Synonyms
    fc39c11 Peptide, wu:fc39c11 Peptide, zgc:110210 Peptide, AF9 Peptide, YEATS3 Peptide, 2210011H10Rik Peptide, 2610012I03Rik Peptide, 3830408D16Rik Peptide, Af9 Peptide, D4Ertd321e Peptide, Af-9 Peptide, MLLT3, super elongation complex subunit Peptide, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3 Peptide, mllt3 Peptide, MLLT3 Peptide, Mllt3 Peptide
    Background
    MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice. Translocation t (9,11)(p22,q23), a chromosomal aberration involving MLLT3 is associated with acute leukemias.

    Alias Symbols: AF9, FLJ2035, YEATS3

    Protein Interaction Partner: AFF1,APPBP2,BCOR,C1orf103,C7orf64,CBX8,EEF1A1,MCM6,MLLT3,PTN,APPBP2,BCOR,C1orf103,C7orf64,DOT1L,EEF1A1,MCM6,PTN,SGK1

    Protein Size: 342
    Molecular Weight
    37 kDa
    Gene ID
    4300
    NCBI Accession
    NM_004529
    UniProt
    Q6LEQ8
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