Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (N-Term) Peptide
NFATC1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NFATC1 products
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NFATC1 antibody (Catalog #: ARP38742_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
- Synonyms
- nf-atc Peptide, nfat2 Peptide, nfatc Peptide, si:ch211-198c22.2 Peptide, NFATC1 Peptide, 2210017P03Rik Peptide, AI449492 Peptide, AV076380 Peptide, NF-ATc Peptide, NFAT2 Peptide, NFATc Peptide, Nfatcb Peptide, NF-ATC Peptide, NF-ATc1 Peptide, NFAT Peptide, NFATmac Peptide, nuclear factor of activated T-cells 1 Peptide, nuclear factor of activated T-cells 1 L homeolog Peptide, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 Peptide, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 Peptide, NFATC1 Peptide, nfatc1.L Peptide, nfatc1 Peptide, Nfatc1 Peptide
- Background
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NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of this protein may regulate inducible expression of different cytokine genes. The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Alias Symbols: MGC138448, NF-ATC, NFAT2, NFATc
Protein Interaction Partner: EP300,GNB2L1,MAPK14,PIM1,PPP3R1,PRKCA,SPI1,EGR1,EGR2,PIM1
Protein Size: 716 - Molecular Weight
- 78 kDa
- Gene ID
- 4772
- NCBI Accession
- NM_172390, NP_765978
- UniProt
- Q2M1S3
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