Nuclear Transcription Factor Y, beta (NFYB) Peptide
NFYB
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NFYB products
- NFYB (Nuclear Transcription Factor Y, beta (NFYB))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NFYB antibody (Catalog #: ARP38748_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NFYB (Nuclear Transcription Factor Y, beta (NFYB))
- Synonyms
- CBF-A Peptide, CBF-B Peptide, HAP3 Peptide, NF-YB Peptide, NFYB Peptide, nfyb Peptide, zgc:110533 Peptide, zgc:110552 Peptide, hap3 Peptide, cbf-a Peptide, cbf-b Peptide, CBFB Peptide, Nfya Peptide, AA985999 Peptide, Cbf-A Peptide, nuclear transcription factor Y subunit beta Peptide, nuclear transcription factor Y subunit beta L homeolog Peptide, nuclear transcription factor Y, beta b Peptide, nuclear transcription factor Y, beta a Peptide, nuclear transcription factor-Y beta Peptide, NFYB Peptide, nfyb.L Peptide, nfybb Peptide, nfyba Peptide, nfyb Peptide, Nfyb Peptide
- Background
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NFYB is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence, protein sequence alignments and experiments with mutants.The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence, protein sequence alignments and experiments with mutants.
Alias Symbols: HAP3, CBF-A, CBF-B, NF-YB
Protein Interaction Partner: MYC,C1QBP,CEBPZ,CIITA,CNTN2,CSDA,DRAP1,ELF1,EP300,MYC,NFYA,NFYC,SP1,TBP,TP53,TP73,YBX1,CEBPZ,CNTN2,DRAP1,MYC,NFYA,TBP,TP73
Protein Size: 207 - Molecular Weight
- 23 kDa
- Gene ID
- 4801
- NCBI Accession
- NM_006166, NP_006157
- UniProt
- P25208
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