Nicotinamide Nucleotide Transhydrogenase (NNT) (N-Term) Peptide
NNT
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all NNT products
- NNT (Nicotinamide Nucleotide Transhydrogenase (NNT))
- Protein Region
- N-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NNT antibody (Catalog #: ARP46892_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NNT (Nicotinamide Nucleotide Transhydrogenase (NNT))
- Synonyms
- Afu5g02780 Peptide, GCCD4 Peptide, 4930423F13Rik Peptide, AI323702 Peptide, BB168308 Peptide, wu:fa20d10 Peptide, wu:fc86a04 Peptide, zgc:76979 Peptide, Nicotinamide Nucleotide Transhydrogenase Peptide, nicotinamide nucleotide transhydrogenase Peptide, nicotinamide nucleotide transhydrogenase L homeolog Peptide, nnt-1 Peptide, AFUA_5G02780 Peptide, nnt Peptide, NNT Peptide, Nnt Peptide, nnt.L Peptide
- Background
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NNT is an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene.
Alias Symbols: MGC126502, MGC126503
Protein Interaction Partner: HNRNPA1
Protein Size: 1086 - Molecular Weight
- 114 kDa
- Gene ID
- 23530
- NCBI Accession
- NM_012343, NP_036475
- UniProt
- Q13423
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