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Nucleolar Protein 6 (NOL6) (N-Term) Peptide

NOL6 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN980794
  • Target See all Nucleolar Protein 6 (NOL6) products
    Nucleolar Protein 6 (NOL6)
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-NOL6 antibody (Catalog #: ARP40994_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Nucleolar Protein 6 (NOL6)
    Synonyms
    NRAP Peptide, UTP22 Peptide, bA311H10.1 Peptide, nrap Peptide, utp22 Peptide, AA410091 Peptide, Nrap Peptide, nucleolar protein 6 Peptide, nucleolar protein 6 L homeolog Peptide, nucleolar protein family 6 (RNA-associated) Peptide, NOL6 Peptide, Nol6 Peptide, nol6.L Peptide
    Background
    NOL6 is a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.

    Alias Symbols: FLJ21959, MGC14896, MGC14921, MGC20838, NRAP, UTP22, bA311H10.1

    Protein Interaction Partner: G3BP1

    Protein Size: 1146
    Molecular Weight
    127 kDa
    Gene ID
    65083
    NCBI Accession
    NM_022917, NP_075068
    UniProt
    Q9H6R4
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