Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) (C-Term) Peptide
NTRK3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NTRK3 products
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NTRK3 antibody (Catalog #: ARP51318_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
- Synonyms
- TRKC Peptide, gp145(trkC) Peptide, trkC Peptide, AW125844 Peptide, Ntrk3_tv3 Peptide, TrkC Peptide, neurotrophic receptor tyrosine kinase 3 Peptide, neurotrophic tyrosine kinase, receptor, type 3 Peptide, NTRK3 Peptide, Ntrk3 Peptide
- Background
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NTRK3 is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Alias Symbols: TRKC, gp145(trkC)
Protein Interaction Partner: DOK5,DYNLL1,HTR2A,IRAK1,JUN,KIDINS220,MAPK1,MAPK3,NGFR,NGFRAP1,NTF3,PLCG1,PTPN1,RASGRF1,SHC1,SHC2,SQSTM1,FRS2,NTF3,PLCG1,PTPN1,SHC1,SQSTM1
Protein Size: 825 - Molecular Weight
- 89 kDa
- Gene ID
- 4916
- NCBI Accession
- NM_002530, NP_002521
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