One Cut Homeobox 2 (ONECUT2) (N-Term) Peptide
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- Target See all ONECUT2 products
- ONECUT2 (One Cut Homeobox 2 (ONECUT2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ONECUT2 antibody (Catalog #: ARP37740_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ONECUT2 (One Cut Homeobox 2 (ONECUT2))
- Synonyms
- C730009D12 Peptide, OC-2 Peptide, Oc2 Peptide, OC2 Peptide, RGD1564677 Peptide, one cut domain, family member 2 Peptide, one cut homeobox 2 Peptide, Onecut2 Peptide, ONECUT2 Peptide
- Background
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ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism. This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.
Alias Symbols: MGC120377, MGC120378, OC-2, OC2
Protein Size: 504 - Molecular Weight
- 54 kDa
- Gene ID
- 9480
- NCBI Accession
- NM_004852, NP_004843
- UniProt
- O95948
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