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One Cut Homeobox 2 (ONECUT2) (N-Term) Peptide

ONECUT2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981137
  • Target See all ONECUT2 products
    ONECUT2 (One Cut Homeobox 2 (ONECUT2))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ONECUT2 antibody (Catalog #: ARP37740_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ONECUT2 (One Cut Homeobox 2 (ONECUT2))
    Synonyms
    C730009D12 Peptide, OC-2 Peptide, Oc2 Peptide, OC2 Peptide, RGD1564677 Peptide, one cut domain, family member 2 Peptide, one cut homeobox 2 Peptide, Onecut2 Peptide, ONECUT2 Peptide
    Background
    ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism. This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.

    Alias Symbols: MGC120377, MGC120378, OC-2, OC2

    Protein Size: 504
    Molecular Weight
    54 kDa
    Gene ID
    9480
    NCBI Accession
    NM_004852, NP_004843
    UniProt
    O95948
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