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Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2) Peptide

PBX2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981411
  • Target See all PBX2 products
    PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PBX2 antibody (Catalog #: ARP32069_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))
    Synonyms
    G17 Peptide, HOX12 Peptide, PBX2MHC Peptide, AU043397 Peptide, pbxy Peptide, wu:fb73g03 Peptide, hox12 Peptide, pbx2mhc Peptide, PBX2P1 Peptide, PBX homeobox 2 Peptide, pre B cell leukemia homeobox 2 Peptide, pre-B-cell leukemia homeobox 2 Peptide, pre-B-cell leukemia homeobox 2 L homeolog Peptide, PBX2 Peptide, Pbx2 Peptide, pbx2 Peptide, pbx2.L Peptide
    Background
    PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t(1,19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1,19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1,19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.

    Alias Symbols: G17, HOX12, PBX2MHC

    Protein Interaction Partner: BAIAP2,BLOC1S1,CCDC88B,CENPBD1,COPS6,DCTN3,HOXA9,HOXB8,IKBKAP,MCRS1,NUP62,PBX1,PBX2,PKNOX1,RPL4,RPS6KC1,SKIV2L2,SMYD3,UBE2E1,ZDHHC7,HOXA9

    Protein Size: 430
    Molecular Weight
    46 kDa
    Gene ID
    5089
    NCBI Accession
    NM_002586, NP_002577
    UniProt
    P40425
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