Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (Middle Region) Peptide
PNRC2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PNRC2 products
- PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NQSWNSSLSG PRLLFKSQAN QNYAGAKFSE PPSPSVLPKP PSHWVPVSFN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PNRC2 Antibody(ARP57028_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))
- Synonyms
- 0610011E17Rik Peptide, D4Bwg0593e Peptide, wu:cegs2777 Peptide, wu:fb51a04 Peptide, wu:fb81a06 Peptide, wu:fd19g06 Peptide, proline rich nuclear receptor coactivator 2 Peptide, proline-rich nuclear receptor coactivator 2 Peptide, PNRC2 Peptide, Pnrc2 Peptide, pnrc2 Peptide
- Background
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PNRC2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery.PNRC2 may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. PNRC2 is required for UPF1/RENT1 localization to the P-body. PNRC2 also acts as a nuclear receptor coactivator. PNRC2 may play a role in controlling the energy balance between energy storage and energy expenditure.
Alias Symbols: FLJ20312, MGC99541
Protein Interaction Partner: AR,ESR1,ESR2,ESRRA,ESRRG,HNF4A,HNF4G,NR5A1,NR5A2,RARA,RARG,RORA,RORB,ZBTB16
Protein Size: 139 - Molecular Weight
- 15 kDa
- Gene ID
- 55629
- NCBI Accession
- NM_017761, NP_060231
- UniProt
- Q9NPJ4
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