Protection of Telomeres 1 (POT1) (Middle Region) Peptide
POT1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all POT1 products
- POT1 (Protection of Telomeres 1 (POT1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MNSENQTMLS LEFHLHGGTS YGRGIRVLPE SNSDVDQLKK DLESANLTAN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-POT1 Antibody(ARP58317_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- POT1 (Protection of Telomeres 1 (POT1))
- Synonyms
- HPOT1 Peptide, POT1 Peptide, DKFZp469P1825 Peptide, pot1 Peptide, 1500031H18Rik Peptide, AI851169 Peptide, Pot1 Peptide, Pot1a Peptide, protection of telomeres 1 Peptide, protection of telomeres 1 L homeolog Peptide, protection of telomeres 1A Peptide, POT1 Peptide, pot1.L Peptide, Pot1a Peptide, Pot1 Peptide
- Background
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This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
Alias Symbols: DKFZP586D211, hPot1, HPOT1
Protein Interaction Partner: ACD,ACD,TERF1,TNKS,ACD,TERF1,TINF2,TNKS
Protein Size: 634 - Molecular Weight
- 70 kDa
- Gene ID
- 25913
- NCBI Accession
- NM_015450, NP_056265
- UniProt
- Q9NUX5
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