Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) (Middle Region) Peptide
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- Target See all PPP1R13B products
- PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PPP1R13B antibody (Catalog #: ARP47979_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
- Synonyms
- ASPP1 Peptide, p53BP2-like Peptide, p85 Peptide, AI449786 Peptide, AW545810 Peptide, Tp53bp2 Peptide, Trp53bp2 Peptide, protein phosphatase 1 regulatory subunit 13B Peptide, protein phosphatase 1, regulatory subunit 13B Peptide, protein phosphatase 1 regulatory subunit 13B L homeolog Peptide, protein phosphatase 1, regulatory subunit 13Bb Peptide, protein phosphatase 1, regulatory (inhibitor) subunit 13B Peptide, PPP1R13B Peptide, Ppp1r13b Peptide, ppp1r13b.L Peptide, ppp1r13bb Peptide, ppp1r13b Peptide
- Background
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PPP1R13B is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
Alias Symbols: ASPP1, KIAA0771, p53BP2-like, p85
Protein Interaction Partner: E2F1,E2F1,E2F2,E2F3,E2F4,PPP1CA,TP63,TP73
Protein Size: 1090 - Molecular Weight
- 119 kDa
- Gene ID
- 23368
- NCBI Accession
- NM_015316, NP_056131
- UniProt
- Q96KQ4
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